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Vitamin B12 is an essential component of a number of enzymes involved in normal metabolism

Shortages may stem from a multitude of sourcesraw material scarcity, supply chain snags, manufacturing line issues, rigorous quality control standards, frequent label changes, inaccurate demand forecasting, and the struggle with slim profit margins

Licensed 503A compounding pharmacies serving PlexusDx follow FDA regulations and quality controls

The accelerated approval was granted based on initial overall response rate (ORR) of 57% in 164 treatment-nave patients and duration of response (DOR)40% of responders had a duration of response greater than 12 months, according to the FDAs full approval announcement

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