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GSH is present at very high concentrations (110 mM) in humans, allowing it to scavenge ROS either directly or indirectly [15]

Both primary and secondary hypogonadism present with persistent low levels of testosterone, but primary hypogonadism is also associated with elevated luteinizing hormone (LH) while secondary hypogonadism may present with low or normal LH

Nevertheless, patients should be advised to report symptoms such as persistent hoarseness, neck swelling, difficulty swallowing, or breathing problems, which warrant prompt medical assessment

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e.g., miR-148a modulates DNMT1 under hypoxia ( Chromatin remodeler ARID1A, critical for endometrial receptivity, is downregulated in eutopic endometrium of women with endometriosis, likely via epigenetic/transcriptional mechanisms rather than mutations