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The three analogues reviewed here solve these problems through different structural strategies and that divergence in design produces divergence in research applications

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Sulfonylureas target ABC transporters (hsa02010), yet these were not identified in the enrichment analysis for AD or DM2, despite their role in drug metabolism, BBB permeability, and -amyloid clearance 79,80

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10.1016/J.YFRNE.2022.100978 [DOI] [PubMed] [Google Scholar] Parga JA, Rodriguez-Perez AI, Garcia-Garrote M et al (2018) Angiotensin II induces oxidative stress and upregulates neuroprotective signaling from the NRF2 and KLF9 pathway in dopaminergic cells