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As depicted in Figure 3D, AICAR treatment significantly inhibited the phosphorylation of PARP-1 while it increased the ABCA1 protein level

Methods: Using a DSS-induced mouse model of colitis, animals were divided into five groups ( n = 8): blank control (CK), model (DSS), low- and high-dose TLYY (TLYYL, TLYYH), and positive control (5-ASA)

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