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Safranal, a monoterpene aldehyde responsible for the characteristic smell of saffron, is an antioxidant that contributes to lowering oxidative stress in the neurons, inhibiting the production of pro-inflammatory cytokines and balancing the equilibrium between free radicals and antioxidants activity (Seyedinia et al., 2023)
GENDER DIFFERENCES IN HPA AXIS REGULATION Endogenous glucocorticoid responses to stress are significantly elevated (in an estrogen-dependent fashion) in females as compared with males (241-244)
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Kupffer cell sensitization by alcohol involves increased permeability to gut-derived endotoxin
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