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This medicine is commonly used under medical supervision for managing nausea and vomiting during pregnancy , morning sickness , and for supporting Vitamin B6 and folic acid supplementation during pregnancy

There are no formal human clinical trials supporting the safety or efficacy of this specific combination

The problems reported above are believed to be rare

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WHO stressed that while the efficacy of the therapies in treating obesity was "evident", it was issuing "conditional recommendations" for use since more data was needed on efficacy and safety over longer periods