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Currently, there is no FDA-approved indication for GLP-1 receptor agonists or GIP/GLP-1 dual agonists specifically for lipedema treatment, and high-quality clinical trial evidence remains limited

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On its face, the same criteria would apply in parity

Your provider may suggest stepping down from 1.0 mg to 0.5 mg weekly, or staying at 1.0 mg if your weight remains stable and you tolerate the medication well

Although exendin-4 still lacked the extended half-life required to be effective for glycemic control, it set the foundation for the development of new GLP-1 analogs relatively resistant to dipeptidyl peptidase-4 with prolonged half-lives revolutionizing the treatment of obesity and type 2 diabetes