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was an investigator for Clinuvel, Estee Lauder, and Ferndale Laboratories and he received equipment from Canfield

doi: 10.3390/cells11060932 264 Souza-FernandesA

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Interestingly, infants with congenital GH deficiency and GHR mutations present with only minor growth retardation, whereas the rare patient with IGF-I deficiency, secondary to a homozygous partial deletion of the IGF-I gene, presents with severe pre and postnatal growth failure, mental retardation, sensorineural deafness, and microcephaly (76-78)

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