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Last Published 05.01.2026 Effective Date: 01.01.2026 This policy addresses the use of interspinous bony fusion devices and interspinous decompression systems

The mechanisms described below reflect current scientific understanding, including data from the 2023 phase 2 trial published in the New England Journal of Medicine (NEJM), as well as preclinical and mechanistic research

Proteins are generally too big and too dependent on correct folding to synthesize that way, so you have to grow them in living cells