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10.1038/S41576-022-00519-Z [DOI] [PMC free article] [PubMed] [Google Scholar] Laposky AD, Bass J, Kohsaka A, Turek FW (2008) Sleep and circadian rhythms: key components in the regulation of energy metabolism

This can translate into: Fewer energy crashes Better focus Improved sleep quality Less inflammation These benefits matter just as much as the number on the scale

Analysis of labeled BCAAs metabolites showed more labeled -Ketoisocaproate (-KIC) and Leu-derived BCKAs in NSCLC cells

L., van den Berg, L

Understanding this timeline helps set realistic expectations and supports treatment adherence during the critical early months of therapy