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This condition may arise due to insufficient dietary intake (resulting from several factors, including: a) the exclusive presence of B12 in animal-derived foods

Because it has mild antibacterial and antifungal properties, apple cider vinegar has earned a reputation for many household and personal uses

The New England journal of medicine 338 , 209216, (1998)

Glucosinolates and their breakdown derivatives (metabolites), especially isothiocyanates and indole-3-carbinol, exert a variety of biological activities that may be relevant to health promotion and disease prevention in humans (see the MIC articles on Indole-3-Carbinol and Isothiocyanates)

Moreover, UV radiation can activate the proopiomelanocortin (POMC) gene and thereby enhance the production of alpha-melanocyte stimulating hormone (-MSH) and adrenocorticotropic hormone (ACTH) which can lead to increased PKA and melanogenesis (Im et al., 2002)