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95,96,124 The TRC8 complex is hijacked by cytomegalovirus (CMV) to target MHC-I for degradation as an immune evasion strategy

Hypoxic tumor cells frequently enter quiescent or slow-cycling states and downregulate homologous recombination and mismatch repair pathways, rendering them intrinsically resistant to DNA-damaging therapies and antimitotic drugs (108, 133, 134)

Furthermore, -actin was used as an internal control

Some ferroptosis-targeting agents have poor pharmacokinetic properties, such as low solubility, high metabolic clearance, low cellular permeability, and short half-lives ( Figure 7 )

Adequate blood supply delivers essential nutrients and oxygen to damaged tissues for recovery