discovery of glp 1 Historical timeline GLP-1 biology, receptor agonist discovery, and Science's 2023 Breakthrough: GLP-1R Agonists

In addition, it can also regulate the expression of genes related to energy metabolism in gut microbes, and BBR changes the level of tryptophan metabolites, increases the species diversity and uniformity of gut microbes reduces the level of aromatic amino acids, and increases the content of probiotics after being metabolized by oxidation, demethylation, and hydrogenation processes in vivo (Liu et al., 2024)

Inflamm Res (2003) 52:30510.10.1007/s00011-003-1178-4 109 Pena-JuarezMCCampos-RodriguezRGodinez-VictoriaMCruz-HernandezTRReyna-GarfiasHBarbosa-CabreraREet alEffect of bovine lactoferrin treatment followed by acute stress on the IgA-response in small intestine of BALB/c mice

doi: 10.1016/0014-5793(94)01430-9 113 RowlandsJHengJNewsholmePCarlessiR

Mats, J

This further supports the theory that the central and peripheral GLP-1 systems are not only anatomically but also functionally distinct