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A slight but significant increase of coumarin-6 uptake by ischemic brains of mice was observed with GSH coated PLGA-PEG nanoparticles when compared with non-GSH coated PLGA-PEG nanoparticles [51]

In addition, it may enhance the effectiveness of other common supplements used to treat arthritis, such as glucosamine sulfate, chondroitin sulfate, and boswellic acid

doi: 10.3389/fpsyt.2020.00172 Received 25 December 2019 Accepted 21 February 2020 Published 18 March 2020 Volume 11 - 2020 Edited by Guillaume Gourcerol, Universit de Rouen, France Reviewed by Juntaro Matsuzaki, University of California, San Francisco, United States

Test items: appearance, content, related substances, microbial limit and sterility