This bi-compartmental signaling distinguishes MOTS-c from other mitochondrial-derived peptides and enables coordinated metabolic responses at both cellular and organismal levels
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Plasma remained clearly separated from both CSF types, whereas lumbar CSF clustered closer to ventricular CSF
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Life Sci 351:122838 Hglinger GU, Adler CH, Berg D, Klein C, Outeiro TF, Poewe W, Postuma R, Stoessl AJ, Lang AE (2024) A biological classification of Parkinsons disease: the SynNeurGe research diagnostic criteria