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for both men and women, with women often under-diagnosed and under-treated according to many studies, as noted by the American Heart Association

It should be used in adults who have been overweight or obese for at least 6 months and have at least one weight-related comorbidity

A key study investigating coagulation factors employed a two-sample Mendelian randomization (MR) approach using large-scale genome-wide association study (GWAS) summary statistics from the UK Biobank (4354 cases, 217,500 controls) and FinnGen (8288 cases, 68,969 controls) cohorts to explore causal associations between 11 coagulation factors and endometriosis risk