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Moreover, a large body of literature exists on the bidirectional relationship between CKD and the circadian clock system, where CKD causes multiorgan or whole-body chronodisruption and the dysfunction of the circadian clock or perturbation of circadian rhythms aggravate CKD and its complications (4)

These side pathwaysnamely the PPP, HBP, and polyol pathwayplay critical roles in regulating redox balance, protein glycosylation, and metabolic stress responses

During June 2014 to November 2021, 211 new triterpenoids were isolated and identified from 8 species of plants in the Schisandraceae family (91)