Zhou Y, Li Y, Zhou T, Zheng J, Li S, Li HB
The carcinogenic risk of GLP-1RAs remains controversial: large-scale cohort studies have not identified an association with pancreatic cancer 36 , but animal experiments suggest that long-term high-dose use may induce ductal hyperplasia 37,38
It represents a promising first-line treatment for DPN, preventing early development and progression through both direct and indirect antioxidant effects [8,23,71,87,110] (Figure 3)
A Phase I oral safety trial has been completed [9] , and a small human case series reported improvements following intra-articular administration [5]
They can help you find the best treatment plan to manage your condition and improve your overall well-being