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Under these conditions, the researchers saw a decrease in Lachnospiraceae family members and Parabacteroides , along with an increase in Enterobacteriaceae species in non-SPF mice receiving a B12-supplemented diet at 200 mg of cyanocobalamin per kilogram [46]

It upregulates growth factors including VEGF and EGF

In this study by Fillon-Emery et al., a multivitamin with folic acid (the synthetic form) was shown to be effective in people with Down syndrome