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The trade-off is a broader side effect profile caused by non-selective receptor activation

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Of all 13 patients, 2 patients suffered some minor wound cellulitis treated with antibiotics alone, one patient had superficial SSI treated with antibiotics and not requiring further intervention, and one patient had deep SSI requiring incision and drainage

For example, alternating weekly between 7.5 mg and 5 mg provides an average dose of 6.25 mg, which may maintain results that previously required continuous 7.5 mg dosing