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Structural similarities have been shown between some EDCs and thyroid hormones (THs) ( Figure 2

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The UK Summary of Product Characteristics (SmPC) for Wegovy and the British National Formulary (BNF) list no direct pharmacokinetic interactions between semaglutide and antidepressants, including SSRIs like sertraline

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In the high-dose group, 93% of participants saw their liver fat drop below the 5% diagnostic threshold after just four months

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As per FMI, the market's valuation is increasingly uncoupled from diabetes prevalence alone, driven by regulatory endorsement of weight management indications and cardiovascular risk reduction claims that expand the addressable patient population by an order of magnitude [1]

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