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Obes (Silver Spring Md) 29(12):20262034 Kolotkin RL, Gadde KM, Peterson CA, Crosby RD (2016) Health-related quality of life in two randomized controlled trials of phentermine/topiramate for obesity: what mediates improvement

Anyone with Wilson's disease or any known copper-metabolism disorder should not use GHK-Cu at all this is the one hard contraindication, topical or injectable

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Your provider will work with you to decide whether to continue at your current dose, make adjustments, or begin tapering off the medication

According to the Ozempic SmPC, the medication works by stimulating glucose-dependent insulin secretion, suppressing glucagon release, and slowing gastric emptying, which prolongs the feeling of fullness after meals