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High-Dose Semaglutide: Balancing Marginal Glycemic Benefits With Tolerability Trade-Offs " El uso de dosis altas de SEMA (ms all de 2 mg/semanal) aporta solo mejoras glucmicas modestas (reduccin adicional de HbA1c de 0,3-0,5%), pero aumenta de forma significativa la prdida de peso (3,4-4,5 kg adicionales) en comparacin con dosis menores
Science 339 , 13201323 (2013)
Mechanisms of action and therapeutic applications of GLP1 and dual GIP/GLP1 receptor agonists
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