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The obtained results were in line with growing evidence suggesting that an imbalance between excitatory and inhibitory neurotransmission, particularly involving glutamate and GABA, is central to ASD pathophysiology (Rubenstein and Merzenich, 2003)

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The catalytic O 2 disproportionation by the material is based on the mechanism of outer-sphere proton-coupled one-electron transfer (the conversion between hydroxo-aquaMn(III) and monoaquaMn(II)), while the catalytic H 2 O 2 disproportionation involves inner-sphere proton-coupled two-electron transfer (the conversion between hydroxo-aquaMn(III) and oxo-hydroxoMn(V))

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J Clin Endocrinol Metab (2017) 102(11):433341