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Clinical trials in patients with chronic venous insufficiency have found that red vine leaf extract (AS 195) reduces leg edema, enhances blood flow, and improves symptoms such as pain and sensation of heaviness and swelling (Stucker 2016

565 Liver-specific Ppar -deficient mice exhibit an enhanced capacity for liver regeneration, mediated by the HGF/c-Met/ERK1/2 signaling pathways

Gross et al., 2014

The role of amino acid transporters in GSH synthesis in the blood-brain barrier and central nervous system

At higher concentrations, MMP2 and MMP9 decrease in ischemic wounds, preventing excessive collagen degradation that would impair healing