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J Pediatr Hematol Oncol 22:581587 Kumar A, Roberts D, Wood KE, Light B, Parrillo JE, Sharma S, Suppes R, Feinstein D, Zanotti S, Taiberg L, Gurka D, Kumar A, Cheang M (2006) Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock

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Other risk factors for the development of toxicity include age (both neonatal and geriatric patients), fever, sepsis and dehydration

[21] BPC 157 has demonstrated favorable results and faster recovery after CHF, but more human studies are needed to confirm this

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