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[15] This complex consists of the following symptoms: Impaired perception of deep touch, pressure and vibration, loss of sense of touch, very annoying and persistent paresthesias Ataxia of dorsal column type Decrease or loss of deep muscle-tendon reflexes Pathological reflexes Babinski, Rossolimo and others, also severe paresis

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Mechanistic underpinnings center on collagen/elastin/GAG upregulation and antioxidant signaling described above