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This makes it more vulnerable to: Collagen loss (leading to wrinkles) Fluid retention (causing puffiness) Pigmentation changes (causing dark circles) Even small lifestyle changes like sleeping late or working under constant stress can make a big difference in how this area looks

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Kirsch, J

Research confirms that without adequate riboflavin (to synthesize FAD for the MAO pathway) and niacin (to provide NAD+ for the ALDH pathway), the body cannot safely clear the toxic intermediate aldehydes generated during the breakdown of histamine, leading to severe cellular toxicity and symptom flares