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Glutathione detoxifies reactive metabolites such as N-acetyl-p-benzoquinone imine (NAPQI)

Biomaterials 294 , 122025 (2023)

doi: 10.1517/17425247.2011.581657 23

In preclinical models, ERR activation: Stimulates expression of genes associated with aerobic exercise adaptation Enhances mitochondrial biogenesis and oxidative respiration Increases fatty acid oxidation in skeletal and cardiac muscle Supports endurance capacity and metabolic flexibility Because of these effects, the compound has been described in the literature as an exercise mimetic a molecule that may reproduce certain biochemical signatures of physical training without the training stimulus itself

Glutatin reductasa La glutatin reductasa ( GR ) conocida tambin como glutatin-disulfuro reductasa ( GSR ) es una enzima que en los seres humanos se encuentra codificada por el gen GSR