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[1] [2] This peptide plays a crucial role in glucose homeostasis by stimulating insulin secretion in a glucose-dependent manner, suppressing glucagon release, and slowing gastric emptying

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Notably, GLP-1 in the OB acts on GLP-1R which are mainly expressed by MCs, which also express receptors for leptin, insulin and ghrelin 43 , further supporting a role for these cells in the control of metabolism 34