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IL-22 selectively and significantly upregulated claudin-2 mRNA expression in organoid cultures and in vivo in the colonic epithelium

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Thus, as circulating L-carnitine concentration increases (as after high-dose intravenous or oral administration of L-carnitine), efficiency of reabsorption decreases and clearance increases, resulting in rapid decline of circulating L-carnitine concentration to baseline

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