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The presence of IgG3 has also been found to predict the treatment response to IVIg, which is thought to work at least partly by saturating FcRn and thereby preventing endogenous IgG from being salvaged from degradation [163, 164]

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Similarly, patients with IDH-wildtype gliomas and 1p/19q non-codeleted tumors consistently displayed lower DRS values compared to their IDH-mutant and 1p/19q codeleted counterparts

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