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This microvascular rarefaction is likely a key contributor to the reduced muscle endurance observed in IGF- 1R KD mice, as capillary networks are critical for sustaining aerobic metabolism and preventing muscle fatigue [58, 62, 63]

Low-dose all-trans retinoic acid enhances cytotoxicity of cisplatin and 5-fluorouracil on CD44+ cancer stem cells

A biofilm was overlaid on an agarose gel to simulate the barriers of chronic wounds and the punctures of the barriers by the MNs were evaluated

The exact mechanism isn't fully understood, but the additional 5-7% weight loss demonstrates GIP's independent contribution beyond GLP-1 alone

Dosing typically ranges from 500 mg to 2.5 g per infusion, administered weekly to monthly depending on clinical goals and response