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Following 68 weeks of once-weekly semaglutide (2.4 mg), participants had achieved an average 17.3% reduction in body weight

Our study highlights the importance of gut microbiota homeostasis for cardiovascular health and suggests that targeted interventions on the gut microbiota may pave the way for innovative preventive and therapeutic strategies targeting atrial cardiomyopathy

The physiological explanation involves metabolic adaptation, where your body adjusts energy expenditure to match reduced caloric intake, temporarily halting weight loss despite continued caloric deficit

This adaptability caters to individual preferences and tolerance levels

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