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Injectable medications ensure controlled hormone delivery, while patches rely on unproven transdermal methods that poorly transport hormone-based compounds

Similarly, people with cystic fibrosis often have weight loss due to malabsorption of nutrients, along with intestinal inflammation

Additionally, a higher percentage of MHT users (45%) also achieved at least 20% total body weight loss, compared to those who didnt use MHT, who saw an 18% total body weight loss

In addition, GSH depletion and GSSG accumulation due to oxidative stress induce apoptosis by activating the SAPK/MAPK pathway [18]