McLean BA, Wong CK, Kaur KD, Seeley RJ, Drucker DJ
Beyond simple actin sequestration, Bock-Marquette and colleagues reported in Nature (2004) that T4 activates integrin-linked kinase and Akt, promoting cardiomyocyte and epicardial cell migration and survival in mouse cardiac injury models, which established a signalling role separate from cytoskeletal buffering
While Ex4 mildly reduced morphine-induced hyperlocomotion, it did not attenuate the expression of morphine-induced CPP, indicating a lack of effect on opioid reward in this model
Sertraline has been tested head to head against drinking outcomes in four randomized trials
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