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However, unlike PD, the average age of patients with IBD with dementia was 65 years, thereby enabling the possibility of future research investigating the functional consequence of an age-dependent reduction in commensal microbial diversity and richness on AD-dementia

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Pretreatment with L-NNA (20 mg/kg i.p.) prior to PTX (10 mg/kg i.p.) produced a small but significant decrease in SOD activity, as compared to PTX-alone and addition of L-arginine (50 mg/kg i.g.) to L-NNA (20 mg/kg i.p.), prior to intraperitoneal PTX application, resulted in the increment of SOD activity similar to that observed in the PTX-treated rats without L-NNA pretreatment ( Fig

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Nausea may occur early, improve with continued treatment, and sometimes become noticeable again after a clinician-directed dose increase

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