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Without sufficient blood supply, cells in the fracture zone do not receive the oxygen and nutrients they need to build new bone

Proc Natl Acad Sci 104(12):49494954 Cao Y, Yan Z, Zhou T, Wang G (2017) SIRT1 regulates cognitive performance and ability of learning and memory in diabetic and nondiabetic models

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26 Pulmonary manifestations include asthma, bronchitis, microaspiration, and pulmonary fibrosis