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MataixJArandaPSnchezCMontellanoMAPlanellsELlopisJ

Steven Dayan, a facial plastic surgeon, recently presented at the IMCAS World Congress in Paris and authored an upcoming article for the Aesthetic Surgery Journal that supports this unique mechanism, which impacts adipose-derived stem cells in the upper layers of the dermis

Evidence-based treatment

Classical T-reg cells produce anti-inflammatory cytokines (TGF- and IL-10) and inhibit activation of Th-1 cells, leading to more anti-inflammatory M2 macrophages

113 , 114 , 115 , 116 Although comparisons between different studies are limited, the proportion of patients who experienced hyperpigmentation was greater than that among those treated with afamelanotide