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In a murine model of DOCA-salt hypertension, BH 4 levels were decreased but could be preserved by endothelial-specific upregulation of GTP cyclohydrolase I, which was associated with a significant reduction in blood pressure

A review on the potential of Resveratrol in prevention and therapy of diabetes and diabetic complications

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Excess ROS production may occur under different circumstances such as smoking (60), leukocytospermia (61), and varicocele (62)