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It just so happened, however, that Ozempic was incredibly effective for weight loss, to the point where it got its own version FDA-approved just for that, Wegovy , and spurred a whole new generation of weight-management medications

For the treatment of noncirrhotic metabolic dysfunction- associated steatohepatitis (MASH), formerly known as nonalcoholic steatohepatitis (NASH), with moderate to advanced liver fibrosis (consistent with stages F2 to F3 fibrosis) in adults

Semaglutide enhances glucose-dependent insulin secretion, suppresses inappropriate glucagon release, delays gastric emptying, and reduces appetite via central nervous system pathways

Most healthcare providers, therefore, prescribe Ozempic off-label, meaning legally but for purposes other than its official intention

With the rise of incretin therapies, two names have emerged as leaders: tirzepatide and semaglutide