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Proteomic analysis was performed to identify differentially expressed proteins (DEPs), while metabolomic profiling was used to characterize metabolic changes

Succinyl-CoA also is required for hemoglobin synthesis.2,4 B12 digestion and absorption requires the adequate synthesis of hydrochloric acid, proteases (enzymes that break down proteins and peptides), and intrinsic factor (a glycoprotein secreted in the stomach)

Microdosing is most useful for patients who are metabolically compromised but not necessarily obese, for those with inflammatory or autoimmune issues, and for individuals who are highly sensitive to medications

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PubMed, Vogt, Anja