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Metabol: clin exp 2011;60:421e9

Mice were dosed every other day for a total of seven treatments, and body weight and food intake were measured daily

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The list of additional contributors includes prenatal and early-life exposures, certain medications, endocrine disorders, gut microbiome alterations, and hypothalamic injuries, all of which may impair energy homeostasis and metabolic regulation [3]

Many of these side effects are manageable and often reduce in severity over time