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NNMT uses up nicotinamide by tagging it with a methyl group (a process called methylation) and sending it out as waste

As I elaborate on in my video The Symptoms of Vitamin B12 Deficiency , these include: Abdominal distention Chronic diarrhea Shortness of breath Swollen, red, painful feet Skin darkening Bilateral useless hand syndrome Numbness and tingling in the hands and feet Muscle cramps Dizziness Cognitive disturbances Difficulty walking Erectile dysfunction Fatigue Depression Psychosis Coma Blindness Vitamin B12 Deficiency Treatment Is A Vitamin B12 Shot Better Than Taking B12 Orally

This is not a complete list of all common or serious side effects

Understanding 5-Amino-1MQ: A Molecule That Helps Preserve NAD+ What Is 5-Amino-1MQ