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Astaxanthin also attenuates the increase in CHOP and ER chaperone protein via the MAPK pathway and inhibits the influx of calcium ions (Grimmig et al., 2019) and upregulates HO-1 via the ERK1/2 pathway to protect against the neurotoxicity of A (Lin et al., 2017)

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What also adds to its legitimacy is transparency

3.5 Respiratory protection In December 2024, tirzepatide received FDA approval for the treatment of moderate-to-severe obstructive sleep apnea (OSA) in obese adults (Beccuti et al., 2024)

Primary culture of mouse tubular cells Primary tubular cells were isolated according to a method previously described 26,27