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GLP-1 receptor activation stimulates adenylyl cyclase, leading to increased intracellular cyclic AMP (cAMP) levels

Results after 8 weeks: Body weight: 8.1% Waist circumference: 8.2% Testosterone: 128.5% (more than doubled) Estrogen: 60.8% Group B Testosterone (TRT) + Lifestyle Medication Used: Transdermal testosterone gel (AndroGel 1.62%) Starting Dose: 23 mg/day, applied to the upper arms/shoulders for the first 14 days