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European Journal of Pharmaceutical Sciences, 102, 2434

457 Disturbances in BCAA metabolism also play a critical role, with elevated BCAA levels detected in failing hearts, likely due to impaired BCAA oxidation during heart failure

Such findings in senescent cell clearance research really matter for anti-aging intervention development, chemotherapy recovery support, and a general understanding of how cellular senescence relates to age-related tissue dysfunction and disease pathogenesis

In parallel with the development of standardised methods for experimental testing, there is an urgent need to establish robust protocols for the analysis of human samples and the accurate quantification of MNPs levels in consumer products and environmental matrices, as these are crucial for defining human-relevant doses in toxicological studies

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