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Clinical implications and practical recommendations In patients with T2DM and established heart failure, SGLT2 inhibitors currently have the strongest evidence base for improving HF outcomes and should be prioritized when not contraindicated [8, 11, 45]

The first-line treatment is surgical resection with wide margins

BioWorld Science Regulatory Endocrine/metabolic Small molecule China FDA IND NMPA

In the future, GLP-1 receptor agonists may also play a role in the management of nondiabetic patients with obesity

The active molecule utilized in research studies is cyanidin 3,5-diglucoside and also juice of Black chokeberry is employed in studies