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Patients who take these drugs long-term can lose more than 15% of their body weight and experience major improvements in blood-sugar control, with reduced risks of heart attacks, strokes, chronic kidney disease, sleep apnea and other obesity-related complications

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DPP-4 InhibitorsMechanism of Action Glucose-dependent insulinotropic peptide is a 42-amino acid gastrointestinal regulatory peptide primarily produced by Kappa () cells located in the duodenum (43, 44)