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Additionally, EMPA may influence immune modulation by shifting macrophage polarization, with some in vivo studies suggesting reduced pro-inflammatory M1 and enhanced anti-inflammatory M2 macrophage populations

through N-term acetylation or C-term amidation

Killion, E

Both work through angiogenesis, which is the formation of new blood vessels, to promote healing in damaged tissues

Regarding metabolic parameters, Cagrilintide treatment did not produce significant changes in HbA1c or fasting plasma glucose from baseline to week 26, while liraglutide 3.0 mg significantly improved both measures, consistent with its known glucose-lowering effects